2nd Bonn Conference on Mathematical Life Sciences - Programme
12:30 - 14:00
Registration with coffee (Foyer)
14:00 - 14:30
Welcome (Lecture hall 2)
14:30 - 16:00
Keynotes
Session chairs: Jan Hasenauer & Kevin Thurley • Lecture hall 2
14:30 - 15:15
Anna Marciniak-Czochra (Institute for Mathematics, University of Heidelberg, Germany)
Space-scale separation and pattern selection in mechano-chemical models of symmetry breaking
15:15 - 16:00
Ursula Klingmüller (Systems Biology of Signal Transduction, German Cancer Research Center (DKFZ), Heidelberg, Germany)
Statistical inference of chromatin- and transcription dynamics in living cells
16:00 - 16:30
Coffee break (Foyer)
16:30 - 18:00
Parallel tracks with invited and selected talks
Modelling of Cellular Pathways 1
Session chair: Jan Hasenauer
Lecture hall 7
16:30 - 17:00
Julio Banga (Computational Biology Lab, MBG-CSIC, Pontevedra, Spain)
Climbing the Ladder of Inverse Problems in Computational Systems Biology
17:00 - 17:15
Sophia Dehnen (Physics Department, University of Freiburg, Germany)
- Condition-Specific Profile Likelihood Analysis: Visualizing how Individual Experimental Conditions Shape Parameter Estimates
17:15 - 17:30
Sebastian Persson (The Francis Crick Institute, London, UK)
- PEtab SciML: The missing layer for scalable and flexible scientific machine learning modeling in biology
17:30 - 17:45
Nicole Radde (Institute for Stochastics and Applications, University of Stuttgart, Germany)
- A population model reveals a surprising role of stochastic cell division in epigenetic memory systems
17:45 - 18:00
Yogesh Bali (Johannes Gutenberg University of Mainz, Germany)
- Mechanochemical Energy Landscapes Under Force: Catch–Slip Bonds in T-Cell Activation
Modelling of Endocrine Systems
Session chair: Maren Philipps
Lecture halls 5+6
16:30 - 17:00
Jae Kyoung Kim (Dept. of Mathematical Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea)
From Blackboard to Bedside: Translating Mathematical Sleep Models into Samsung Galaxy Watch
17:00 - 17:15
Belinda Lombard (School of Mathematics, University of Birmingham, UK)
- Regulation of ultradian pulsatility and stress responses in the human HPA axis
17:15 - 17:30
Chloé Weckel (BIOS, PRC, UMR CNRS, Université de Tours, Centre INRAE Val de Loire, Nouzilly & MUSCA, Université Paris-Saclay, Inria Centre Saclay–Île-de-France, Palaiseau, France)
- Spatiotemporal modeling of signaling pathways: impact of endosomal compartmentalization and application to gonadotropin receptors
17:30 - 17:45
Rafael Arutjunjan (Institute of Physics, University of Freiburg, Germany)
- Adapting Confidence Thresholds and Profile Likelihood Analysis to Small Sample Sizes
17:45 - 18:00
Celvic Coomber (Explainable AI for Biology, Zuse Institute Berlin & Technische Universität Berlin, Germany)
- Investigating endogenous opioids unravels the mechanisms behind opioid induced constipation, a mathematical modeling approach
Mathematical Biology 1
Session chair: Juan Velázquez
Lecture halls 3+4
16:30 - 17:00
Marie Doumic-Jauffret (Inria & École Polytechnique, Center for Applied Mathematic, Merge project-team, France)
Mathematical modelling to unravel the link between senescence and telomere length dynamics
17:00 - 17:15
Carola Sophia Heinzel (Department for Mathematical Stochastics, University of Freiburg, Germany)
- Statistical Test to compare the Linkage Model and the Admixture Model based on Central Limit Results
17:15 - 17:30
Saeed Salehi (Biosystems and Bioprocess Engineering Group, Bio2Eng, IIM-CSIC, Vigo, Spain & BioTeC+, Chemical and Biochemical Process Technology and Control, KU Leuven, Ghent, Belgium)
-
Understanding When Lotka–Volterra Models Fail in Microbial Community Analysis
17:30 - 17:45
Alexander Browning (University of Melbourne, Australia)
-
Heterogeneity in temporally fluctuating environments
17:45 - 18:00
Torkel Loman (University of Oxford, UK)
- Parametric and Functional Identifiability for Universal Differential Equations
from 18:00
Welcome reception (Foyer)
8:30 - 9:00
Welcome coffee (Foyer)
9:00 - 10:30
Keynotes
Session chair: Jan Hasenauer • Lecture hall 2
9:00 - 9:45
Bernd Bodenmiller (Department of Quantitative Biomedicine, University of Zurich & Institute for Molecular Health Sciences, ETH Zürich, Switzerland)
Highly multiplexed imaging of tissues with subcellular resolution by imaging mass cytometry
9:45 - 10:30
Helen Byrne (Mathematical Institute, University of Oxford, UK)
Understanding the shape of vascular networks using topological data analysis
10:30 - 11:00
Coffee break (Foyer)
11:00 - 12:30
Parallel tracks with invited and selected talks
Bioinformatics and Biostatistics 1
Session chairs: Lea Seep & Jan Hasenauer
Lecture hall 7
11:00 - 11:30
Xin Lai (Faculty of Medicine and Health Technology, Tampere University, Finland)
- HallmarkGraph: a cancer hallmark informed graph neural network for classifying hierarchical tumor subtypes
11:30 - 11:45
Alina Schenk (Institute for Medical Biometry, Informatics and Epidemiology (IMBIE), University Hospital Bonn, Germany)
- A regularized Cox model for selecting interactions and time-varying covariate effects
11:45 - 12:00
Oliver Lemke (Institute of Biochemistry, Charité - Universitätsmedizin Berlin, Germany)
- The role of metabolism in shaping enzyme structures over 400 million years of evolution
12:00 - 12:15
Franziska Kimmig (Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Germany)
- Molecular signatures of post-acute sequelae of COVID-19
12:15 - 12:30
Roy Gusinow (Life & Medical Sciences-Institut (LIMES) & Bonn Center for Mathematical Life Science, University of Bonn, Germany)
- Federated Latent Transition Models for Post-Acute Infection Syndromes
Tumor Microenvironment 1
Session chair: Kevin Thurley
Lecture halls 5+6
11:00 - 11:30
Nils Blüthgen (Institute for Theoretical Biology, Charité – Universitätsmedizin Berlin & Humboldt-Universität zu Berlin, Germany)
Modeling latent variables in pooled single cell screens unveils clinically relevant transcriptional modules induced by oncogenes
11:30 - 11:45
Lara Schmalenstroer (Bioinformatics & Computational Biophysics, University of Duisburg-Essen, Germany)
- Mathematical Modeling of Persistent Treatment Responses After Targeted Radiotherapy in Cancer
11:45 - 12:00
Luke De Bretton-Gordon (Mathematical Institute, University of Oxford, UK)
- An Interdisciplinary Approach to Quantifying the Impact of T-Cell Exhaustion on the Tumour Microenvironment
12:00 - 12:15
Madhuri Majumder (The Hebrew University of Jerusalem, The Alexander Silberman Institute of Life Sciences, Israel)
- Modulatory Principles of Cellular Interactions in Hierarchical Cell Organization
12:15 - 12:30
Lukas Kiwitz (Institute of Experimental Oncology, University Hospital Bonn, Germany)
- Quantitative analysis of CODEX multiplexed histological imaging data in the tumour microenvironment
Infectious Disease Modelling 1
Session chair: Martin Kühn
Lecture halls 3+4
11:00 - 11:15
Maylis Layan (Institut Pasteur, Université de Paris, France)
- Impact of the COVID-19 pandemic on the acquisition of ESBL-producing Klebsiella pneumoniae in hospitals: a modelling study on the intensive care unit of Guadeloupe
11:15 - 11:30
Alan Rendall (Institute of Mathematics, Johannes Gutenberg University Mainz, Germany)
- Backward bifurcations and multistationarity
11:30 - 11:45
Julia Bicker (Institute of Software Technology, German Aerospace Center (DLR), Cologne, Germany)
- A hybrid approach for the simulation of spatially-resolved susceptible-infected-recovered epidemics using the method of moments for stochastic reaction networks
11:45 - 12:00
Marvin Schulte (Fraunhofer Institute for Industrial Mathematics ITWM, Division Processes and Materials, Kaiserslautern, Germany)
- The influence of the mutation process on the long-term behavior of infectious diseases
12:00 - 12:15
Burcu Gürbüz (Institute of Mathematics, Johannes Gutenberg University Mainz, Germany)
- Modeling time-dependent vaccine efficacy and re-vaccination dynamics in an extended SIRS framework
12:15 - 12:30
Shrichand Bhuria (Quantitative methods in public health (METIS), École des hautes études en santé publique (EHESP) Rennes, France)
- Modelling the Spread of Healthcare-Associated Infections through a Nationwide Patient-Based Network in France’s Healthcare Settings
12:30 - 13:45
Lunch (University canteen - CAMPO)
13:45 - 15:15
Parallel tracks with invited and selected talks
Modelling of Cellular Pathways 2
Session chair: Daniel Weindl
Lecture hall 7
13:45 - 14:15
Andreas Raue (Department of Applied Computer Science and Medicine, University of Augsburg, Germany)
The Translational Gap in Mechanistic Modeling
14:15 - 14:30
Jenny Geiger (Institute of Cell Biology and Immunology, University of Stuttgart, Germany)
- Stochasticity contributes to explaining heterogeneity in mitochondrial engagement during apoptosis
14:30 - 14:45
Rifaldy Fajar (AI-BioMedicine Research Group, IMCDS-BioMed Research Foundation, Indonesia)
- Mathematical Modeling of Canonical–Noncanonical NF-ΚB Crosstalk Driving Early CD8+ T-Cell Fate Bifurcation and Long-Term Effector–Memory Balance
14:45 - 15:00
Gesina Menz (Department of Information Technology, Uppsala University, Sweden)
- Multi-Framework Modelling of Population-Level Cellular Signalling
15:00 - 15:15
Mio Heinrich (CIBSS Centre for Integrative Biological Signalling Studies & Freiburg Center for Data Analysis and Modeling, University of Freiburg, Germany)
- Flavours of Practical Identifiability: Sensitivities, Confidence, and Confusion
Mathematical Biology 2
Session chair: Kevin Thurley
Lecture halls 5+6
13:45 - 14:00
Hugo Dourado (Heinrich Heine University, Düsseldorf, Germany)
- Growth Mechanics and the oscillatory biomass allocation in self-replicating cells
14:00 - 14:15
Lisa Li (Institute of Experimental Oncology, University Hospital Bonn, Germany)
- Towards data-based mathematical models of spatiotemporal immune-cell interactions
14:15 - 14:30
Gayathri Ramesan (Max Planck Institute
for Neurobiology of Behavior — caesar, Bonn, Germany)
-
Critical dynamics generates slow manifolds for timing in neural networks
14:30 - 14:45
Francis Tetteh Batsa (African Institute for Mathematical Sciences Ghana)
- A Fractional Derivative Approach to Model Anomalous Mass Transport in Atherosclerosis Plaque Formation
14:45 - 15:15
Becca Asquith (Department of Infectious Disease, Imperial College London, UK)
KIRs and T cell dynamics
Infectious Disease Modelling 2
Session chair: Martin Kühn
Lecture halls 3+4
13:45 - 14:00
Nils Gubela (Mathematics of Data Sciences, Freie Universität Berlin, Germany)
- Modelling transient behaviour changes during the 2022 mpox outbreak using temporal adaptive networks
14:00 - 14:15
Alexandra Teslya (University Medical Center Utrecht, Utrecht University, The Netherlands)
- From Classrooms to Communities: Modeling the Impact of School-Based Interventions for Future Pandemic Response
14:15 - 14:30
Fredrick Asenso Wireko (Department of Mathematics, Kwame Nkrumah University of Science and Technology, Ghana)
- Fractional-Order Modelling and Data-Driven Analysis of Lymphatic Filariasis Dynamics in Ghana
14:30 - 14:45
Sydney Paltra (Faculty V - Mechanical Engineering and Transport Systems, Technical University Berlin, Germany)
- Inferring Mobility Reductions from COVID-19 Disease Spread along the Urban-Rural Gradient
14:45 - 15:00
Henrik Zunker (Institute of Software Technology, German Aerospace Center (DLR), Cologne, Germany)
- A semi-continuous Graph-ODE approach with flow-based formulations to avoid quadratic system growth in Lagrangian metapopulation models
15:00 - 15:15
Punya Alahakoon (Pandemic Sciences Institute, University of Oxford, UK)
- Enhancing epidemiological parameter inference using quantitative diagnostic data
15:15 - 16:30
Poster session 1 (odd numbers)
with coffee break (Foyer & seminar room 1-4)
from 17:00
Social event (Arithmeum, "Haus der Geschichte or Bonn city center)
8:30 - 9:00
Welcome coffee (Foyer)
9:00 - 10:30
Keynotes
Session chair: Kevin Thurley • Lecture hall 2
9:00 - 9:45
Christoph Zechner (Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy)
Advancement of dynamic pathway modelling towards clinical translation
9:45 - 10:30
Dominic Grün (Institute of Systems Immunology, University of Würzburg, Germany)
Decoding the cellular circuitry of organ tissues
10:30 - 11:00
Coffee break (Foyer)
11:00 - 12:30
Parallel tracks with invited and selected talks
Tumor Microenvironment 2
Session chair: Marieta Toma
Lecture hall 7
11:00 - 11:15Federica Eduati (Eindhoven University of Technology, The Netherlands)
- Integrating spatial imaging and intracellular signaling to model emergent tumor–T cell dynamics with multiscale agent-based models
11:15 - 11:30Paras Jain (Indian Institute of Science, Bangalore, India)
- Modeling Epithelial-Mesenchymal Plasticity: A Driver of Immune Evasion in Cancer
11:30 - 11:45
Prihantini Prihantini (AI-BioMedicine Research Group, IMCDS-BioMed Research Foundation, Indonesia)
- Mathematical Modeling of RNA Velocity Manifold Dynamics Identifies Immune–Metastatic State Transitions and Tertiary Lymphoid Structure Stability Landscapes in Hepatocellular Carcinoma
11:45 - 12:00
David Cicchetti (Radboud University, Nijmegen, The Netherlands)
- Creating Realistic and Controllable Synthetic Tumor Microenvironment Images Using Diffusion Models Conditioned on Simulation Images
12:00 -12:15
Qianci Yang (Max Planck Institute for Evolutionary Biology, Plön, Germany)
- Stochastic Evolution of Resistance in Acute Lymphoblastic Leukemia
12:15 -12:30
Alireza Dostmohammadi (Department of Bioinformatics and Computational Biophysics, Faculty of Biology and Centre for Medical Biotechnology (ZMB), University of Duisburg-Essen, Essen, Germany)
- Spatially Resolved Transcriptomics Reveals Microenvironment-Driven Heterogeneity in Cutaneous T-Cell Lymphoma
Single-Cell Analysis 1
Session chair: Lisa Steinheuer
Lecture halls 5+6
11:00 - 11:30
Alexander Skupin (Integrative Cell Signalling, Luxembourg Centre for Systems Biomedicine (LCBS), University of Luxembourg)
Cell Fate Dynamics at Single-Cell Resolution Reveals Biological Mechanisms in Health and Disease
11:30 - 11:45
Yang Zhao (Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden)
- Spatially resolving B cell clonal dynamics in human and murine tissues
11:45 - 12:00
Nadine van de Brug (Computer Science, Vrije Universiteit Amsterdam, The Netherlands)
- Mapping cellular states over time using a hierarchical feature expectation maximization approach for Gaussian mixture modeling
12:00 - 12:15
Alexander Aivazidis (Genome Biology, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany)
- STORMI leverages CRISPR interventions, DNA sequence syntax and multi-lineage dynamics to infer the regulatory mechanisms governing cell state dynamics
12:15 - 12:30
Isabel Mensah (Department of Mathematics, Kwame Nkrumah University of Science and Technology, Ghana)
- WAVDeSc: A Wavelet Based Denoising Pipeline for single-cell RNA Sequencing Data Analysis
Mathematical Biology 3
Session chair: Kevin Thurley
Lecture halls 3+4
11:00 - 11:30
Luciano Marcon (Andalusian Center for Developmental Biology, Spain)
The Network Basis of Pattern Formation: A Topological Atlas of Multifunctional Turing Networks
11:30 - 12:00
Miri Adler (The Hebrew University of Jerusalem, The Alexander Silberman Institute of Life Science, Israel)
Introducing Hot and Cold Fibrosis: Insights from a Cell-Circuit Theory of Tissue Organization
12:00 - 12:15
Harshavardhan BV (IISc Mathematics Initiative, Indian Institute of Science, India)
- Emergent dynamics of cellular decision making in multi-node mutually repressive regulatory networks
12:15 - 12:30
Inge Wortel (Institute for Computing and Information Sciences, Radboud University, Nijmegen, The Netherlands)
- Cooperative motility emerges in crowds of T cells but not neutrophils
12:30 - 13:45
Lunch (University canteen - CAMPO)
13:45 - 15:00
Special invited talks
Session chair: Jan Hasenauer • Lecture hall 2
13:45 - 14:10
Andreas Reichel (Bayer AG, R&D - Preclinical Development, Berlin, Germany)
Mechanistic PK/PD Modelling of Targeted Protein Degradation: Transforming the Discovery of a Novel Therapeutic Modality
14:10 - 14:35
Heinrich Huber (Boehringer Ingelheim RCV GmbH & Co KG, Division Drug Discovery Sciences, Vienna, Austria)
Translational Insights from Semi‑Mechanistic Modelling of Tumour Growth
14:35 - 15:00
Lorenzo Contento (Pumas-AI Inc.)
A Deep Dive into Generative Scientific Machine Learning
15:00 - 15:45
Plenary discussion
Mathematical life sciences in the age of LLMs and AI bots
Lecture hall 2
15:45 - 17:00
Poster session 2 (even numbers)
with coffee break (Foyer & seminar room 1-4)
17:00 - 18:30
Parallel tracks with invited and selected talks
Modelling of Cellular Pathways 3
Session chair: Stefan Engblom
Lecture hall 7
17:00 - 17:30
Federico Bocci (Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University, Nijmegen, The Netherlands)
Navigating the attractor landscape of single cells
17:30 - 17:45
Paolo Odello (Netherlands Cancer Institute (NKI), Computational Cancer Biology Group, Amsterdam, The Netherlands)
- Dissecting the efficacy of Multiple Low Dose Efficacy via computational modelling of EGFR-MAPK inhibition
17:45 - 18:00
Jeanne Le Clézio (Centre national de la recherche scientifique (CNRS) & Université Côte d'Azur, Laboratoire de Physiomédecine Moléculaire (LP2M), France)
- Physical-Chemistry of Cell Physiology: a top-down, transdisciplinary approach from obvious biological statements to interwoven multiscale algebraic dynamical systems and the need for a tractable mathematical framework
18:00 - 18:15
Rune Höper (Statistical Physics of Evolution, University of Leipzig, Germany)
- A Manually-Curated Stoichiometric Core Model Of Liver Metabolism
18:15 - 18:30
Simon Beyer (Institute of Physics, University of Freiburg, Germany)
- Quantitative Modeling Reveals Feedback Control of T Cell Receptor Trafficking and Surface Homeostasis
Single-Cell Analysis 2
Session chair: Alexander Skupin
Lecture halls 5+6
17:00 - 17:30
Pawel Paszek (Institute of the Fundamental Technological Research - Polish Academy of Sciences, Warsaw, Poland)
Memory, noise and infection: single-cell insights into innate immunity
17:30 - 17:45
Stanislaus Stein (BioQuant, University of Heidelberg, Germany)
- Geometric Modeling of Developmental Velocities in Single-Cell Data
17:45 - 18:00
James Boyle (Mathematical Institute, University of Oxford, UK)
- Inferring Cell-Cell Dynamics from Cell Trajectory Data Using Deep Attention Networks, and the Mechanisms Underlying T Cell Behavioural Heterogeneity in the Response to Cancer
18:00 - 18:15
Clémence Fournié (MAP5 laboratory, Université Paris Cité, France)
- Cell Trajectory Inference based on Schrödinger problem and a mechanistic model of stochastic gene expression
18:15 - 18:30
Tim Stohn (Vrije Universiteit Amsterdam, The Netherlands)
- Detecting changes in protein-covariation in smooth cell-state changes
Mathematical Biology 4
Session chair: Juan Velázquez
Lecture halls 3+4
17:00 - 17:15
Jonas Braß (Institute for Computer Science and Department of Biology, Heinrich Heine University, Düsseldorf, Germany)
- Mechanistical modelling of C4 plants - hydraulics model
17:15 - 17:30
Kumaran Bala Kandan Viswanathan (Radboud University, Nijmegen, The Netherlands)
- Simulation-Driven Representation Learning for Cell Motility Data
17:30 - 17:45
Nils Becker (Theoretical Systems Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany)
- Inference from Phylogenetic Somatic Variant Trees
17:45 - 18:00
Jan Rombouts (Unit of Theoretical Chronobiology, Université Libre de Bruxelles, Belgium)
- Geometry, timescales and boundaries affect aggregation-based patterning in multicellular systems
18:00 - 18:15
Madhumita Mondal (Homi Bhabha National Institute (HBNI), The Institute of Mathematical Sciences (IMSc), India)
- Node persistence from topological data analysis reveals changes in brain functional connectivity
18:15 - 18:30
Adrien Jolly (Department of Medicine 2, Hematology/Oncology, Goethe University Frankfurt, Germany)
- Dynamical modeling-informed interpretation of Ki67 positivity
from 19:30
Conference dinner
8:30 - 9:00
Welcome coffee (Foyer)
9:00 - 10:30
Keynotes
Session chair: Elena Reckzeh • Lecture hall 2
9:00 - 9:45
Christina Leslie (Computational & Systems Biology, Memorial Sloan Kettering Cancer Center, New York, USA)
Decoding cell dynamics and spatial organization in immune responses and the tumor microenvironment
9:45 - 10:30
Jeroen van Zon (AMOLF, Department of Autonomous Matter, Amsterdam, The Netherlands)
AI-driven single-cell tracking of homeostasis in organoids
10:30 - 11:00
Coffee break (Foyer)
11:00 - 12:30
Parallel tracks with invited and selected talks
Bioinformatics and Biostatistics 2
Session chair: Lea Seep
Lecture hall 7
11:00 - 11:15
Laura Koebbe (Institute for Human Genetics, University Hospital Bonn, Germany)
- Rare functional variants in FBN2 are strong genetic determinants for bicuspid aortic valve disease
11:15 - 11:30
Cong Quan Ta (Systems Biology of Signal Transduction, German Cancer Research Center (DKFZ), Heidelberg & Department of Applied Computer Science and Medicine, University of Augsburg, Germany)
- Integration of proteomics data from cell lines and tumors to profile patient drug sensitivity
11:30 - 11:45
Lea Weber (Theoretical Systems Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany)
- Reconstructing Stem-Cell Population Dynamics from Somatic-Mutation Phylogenies in Ageing Mice
11:45 - 12:00
Diego Valderrama (Fraunhofer Institute for Algorithms and Scientific Computing SCAI, St. Augustin, Germany)
- MultiNSDEs: Dose-Guided Neural SDEs for Simulating Real and Counterfactual Patient Trajectories
12:00 - 12:15
Lotta Eriksson (Department of Mathematical Sciences, Chalmers University of Technology & University of Gothenburg, Sweden)
- Sensitive detection of copy number alterations in low-quality liquid biopsy sequencing data
12:15 - 12:30
Manuel Huth (Life & Medical Sciences Institute (LIMES) & Bonn Center for Mathematical Life Science, University of Bonn, Germany)
- NoLimits.jl: A flexible Julia framework for nonlinear and latent-state mixed-effects modeling
Organoids and Stem Cell Biology
Session chair: Elena Reckzeh
Lecture hall 7
11:00 - 11:15
Stefan Engblom (Department of Information Technology, Division of Scientific Computing, Uppsala University, Sweden)
- From single cells to tumors: computational modeling and analysis of cell populations
11:15 - 11:30
Millicent Afrifa Opoku (African Institute for Mathematical Sciences Ghana)
- Geometry-dependent FGF4-ERK signalling drives epiblast-primitive endoderm proportioning in a Cellular Potts model of the human blastocyst
11:30 - 11:45
Lutz Brusch (Center for Interdisciplinary Digital Sciences, Technische Universität Dresden, Germany)
- Virtual Embryo: Blastocyst and Organoid Models in the Morpheus Simulation Framework
11:45 - 12:00
Xuan Zheng (Hubrecht Institute, Utrecht, The Netherlands)
- Organoid cell fate dynamics in space and time
12:00 - 12:15
Ingmar Glauche (Institute for Medical Informatics and Biometry (IMB), TU Dresden, Germany)
- From data to dynamics: mechanistic models illuminate the clonal evolution of hematopoietic stem cells
12:15 - 12:30
Jasmitha Boovadira Poonacha (Life & Medical Sciences Institute (LIMES), University of Bonn, Germany)
- Influence of Culture Media Composition on Drug Sensitivity in CRC organoids
Mathematical Biology 5
Session chair: Nick Monk
Lecture hall 7
11:00 - 11:30
Stephen Moore (University of Cape Coast, Cape Coast, Ghana)
Retrospective Impact Quantification of Malaria Interventions in Ghana
11:30 - 11:45
Henrik Häggström (Department of Mathematical Sciences, Chalmers University of Technology & University of Gothenburg, Sweden)
- Simulation-based inference for stochastic nonlinear mixed-effects models with applications in systems biology
11:45 - 12:00
Mike van Santvoort (Department of Mathematics and Computer Science, Eindhoven University of Technology, The Netherlands)
- Modelling cell-cell interactions with random graphs
12:00 - 12:15
Gloria Agyeiwaa Botchway (Department of Mathematics, University of Ghana, Legon-Accra, Ghana)
- On a modified Leslie-Gower model with prey defense and predator cannibalism
12:15 - 12:30
Johannes Textor (Institute for Computing and Information Sciences, Radboud University, Nijmegen, The Netherlands)
- What Does the Shape Space of T-Cell Epitopes Look Like?
12:30 - 13:00
Closing (Lecture hall 2)